Center for Cancer Cell Biology, Immunology, and Infection
Our interdisciplinary team investigates 1) The cellular and molecular basis of cancer, 2) The role of inflammation in cancer, autoimmunity, and immune-mediated diseases (for example MS, IBD, and obesity), 3) the etiological agents of infectious diseases, and 4) novel mechanisms of host-pathogen interactions.
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Joseph M. Reynolds, PhD
Interim Director, Center for Cancer Cell Biology, Immunology, and Infection
- Joseph Reynolds - Interim Director
- The role of the IL-17 family of cytokines in autoimmune inflammation and mucosal immunity.
- Kwang Poo Chang
- The Leishmania based photo-vaccines against infectious and malignant diseases.
- Svetlana Dambaeva
- Immune response at the maternal-fetal interface and analysis of immune mechanisms of infertility and recurrent pregnancy loss
- Joseph X. DiMario
- The cellular and molecular mechanisms that regulate the development and differentiation of skeletal muscle fibers and their respective phenotypes.
- Mirek Dundr
- Compartmentalization of the nucleus as it contributes to genome function and regulates genome organization in cancer.
- David N. Everly
- Epstein-Barr virus (EBV) transforming protein and its role in manipulating cellular signaling pathways involved in tumor formation (Note: EBV is associated with Burkitt’s lymphoma, nasopharyngeal carcinoma, as well as certain types of Hodgkin disease and gastric cancers).
- Constitutive inflammatory signaling in virally induced cancer and the role of viruses in multiple sclerosis.
- Johnny J. He
- HIV infection and pathogenesis in astrocytes
- Molecular mechanisms of HIV Tat protein neurotoxicity
- Tip110 and tumorigenesis
- Hongkyun Kim
- Identification and characterization of genes responsible for neuromuscular diseases, including muscular dystrophies.
- Ying Liu
- HIV latency in astrocytes.
- Tip110 and HIV gene transcription control.
- Fabio Re
- The role of toll-like receptors and inflammasomes during bacterial infections and vaccination.
- Neelam Sharma-Walia
- Arachidonic acid pathway in KSHV pathogenesis.
- The role of inflammatory COX-2 and lipoxins and anti-inflammatory leukotrienes role in inflammatory breast cancer and virus associated cancers.
- Rahul Vijay
- The precise role played by the early short-lived plasmablasts in various infections.
- Identification of immunotherapeutic approaches to restrain infection-induced plasmablasts.
- Carl White
- Modulation of reactive oxygen species and calcium signaling pathways in the smooth muscle cells of resistance arterioles in mouse models of diabetes.