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Academic Year 2016-2017 Publications and Grants

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Academic Year 2015-2016 Publications and Grants

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Table of Contents

Chicago Medical School

Biochemistry and Molecular Biology

Peer-Reviewed Publications

Thompson AM, Ursu O, Babkin P, et al. Discovery of a specific inhibitor of human GLUT5 by virtual screening and in vitro transport evaluation. Sci Rep. 2016; 6:24240.

Radchenko M, Nie R, Lu M. Disulfide crosslinking of a multidrug and toxic compound extrusion transporter impacts multidrug efflux. J. Biol. Chem. 2016; 291:9818-9826.

Zhu J, Liu X, Anjos M, Correll CC, Johnson AW. Utp14 recruits and activates the RNA helicase Dhr1 to undock U3 snoRNA from the pre-ribosome. Molecular and Cellular Biology. 2016; 36(6):965-978.

Jordan P, Choe JY, Boles E, Oreb M. Hxt13, Hxt15, Hxt16 and Hxt17 from Saccharomyces cerevisiae represent a novel type of polyol transporters. Sci Rep. 2016; 6:23502.

Lu M. Structures of multidrug and toxic compound extrusion transporters and their mechanistic implications. Channels. 2016; 10: 88-100.

Woitowich NC, Philibert KD, Leitermann RJ, Wungjiranirun M, Urban JH, Glucksman MJ. EP24.15 as a Potential Regulator of Kisspeptin Within the Neuroendocrine Hypothalamus. Endocrinology. 2016;157(2):820-30.

Choe JY. Artist's Statement: Crystallography as Art. Acad Med. 2015; 90(12):1631.

Symersky J, Guo Y, Wang J, Lu M. Crystallographic study of a MATE transporter presents a difficult case in structure determination with low-resolution, anisotropic data and crystal twinning. Acta Cryst. 2015; D71:2287-2296.

Thompson AG, Iancu CV, Nguyen TT, Kim D, Choe JY. Inhibition of human GLUT1 and GLUT5 by plant carbohydrate products; insights into transport specificity. Sci Rep. 2015; 5:12804.

Radchenko M, Symersky J, Nie R, Lu M. Structural basis for the blockade of MATE multidrug efflux pumps. Nat. Commun. 2015; 6:7995.

Burdette D, Gross A. Spin Labeling of Potassium Channels. Methods Enzymol. 2015; 564:389-400.

Cell Biology and Anatomy

Peer-Reviewed Publications

Havens MA, Hastings ML. Splice-switching antisense oligonucleotides as therapeutic drugs. Nucleic Acid Res. 2016.

Sawyer IA, Shevtsov SP, Dundr M. Spectral imaging to visualize higher-order genomic organization. Nucleus. 2016; 7(3), PMID:27167405.

Wang Q, Sawyer IA, Sung MH, et al. Cajal bodies are linked to genome conformation. Nature Communications. 2016; doi: 10.1038/ncomms10966.

Hinrich AJ, Jodelka FM, Chang JL, et al. Therapeutic correction of ApoER2 splicing in Alzheimer’s disease mice using antisense oligonucleotides. EMBO Mol. Med. 2016; 8:328-345.

Li P, Janczewski WA, Yackle K, et al. The peptidergic control circuit for sighing. Nature. 2016; 530(7590): 293-7.

Weimer K, DiMario JX. Muscle fiber type specific activation of the slow myosin heavy chain 2 promoter by a non-canonical E-box. Biochem. Biophys. Res. Comm. 2016; 469:842-847.

Frost WN, Brandon CJ, Bruno AM, et al. Monitoring spiking activity of many individual neurons in invertebrate ganglia. Adv. Exp. Med. Biol. 2015;859:127-145.

Hill ES, Vasireddi SK, Wang J, Bruno AM, Frost WN. Memory formation in Tritonia via recruitment of variably-committed neurons. Current Biology. 2015; 25(22): 2879-2888.

Books, Book Chapters, and Review Articles

Sarras MP Jr, Leontovich AA, Intine RV. A Potential gDNA Methylation Epigenetic Mechanism to Explain the Long Term Complications of Type 1 and 2 Diabetes. Anat. and Physiology. 2016.

Frost WN. The swimming sea anemone Stomphia. In: Tide Bites. 2015; 24: 1-3.

Kim H, Oh KH. Protein network interacting with BK channels. In: Contet C (ed). Big on BK: Current Insights into the Function of Large Conductance Voltage- and Ca2+- Activated K+ Channels at the Molecular, Cellular and Systemic Levels, International review of neuroscience. Elsevier Press; 2016.

Sawyer IA, Dundr M. Nuclear bodies: Built to boost. J Cell Biol. 2016; 213(5), doi: 10.1083/jcb.201605049.

Geraets RD, Hastings ML, Kielian T, Pearce DA, Weimer JM. Moving Towards effective therapeutic strategies for neuronal ceroid lipofuscinosis. Orphanet J Rare Dis. 2016; 11, 40.

Case AM, Sawyer IA, Dundr M, Hastings ML. Pre-mRNA Splicing: Function and Dysfunction. In: Bradshaw RA, Stahl PD, eds. Encyclopedia of Cell Biology, Volume 1: Molecular Cell Biology. Elsevier; 2016:503-511. ISBN: 978-0-12-394796-3.

Sarras MP Jr, Leontovich AA, Intine RV. Use of Zebrafish as a model to investigate the role of epigenetics in propagating the secondary complications observed in Diabetes mellitus. Comparative Biochemistry and Physiology. 2015; Part C 178: 3-7.

Sarras MP Jr. Editorial Overview of the Current Issue of Anatomy and Physiology. Anatomy and Physiology. 2015; 1(4), 1-2.

Sarras MP Jr, Intine RV. The Role of DNA Methylation in Type 1 and 2 Diabetes as Related to Endothelial Cell Dysfunction. Anatomy and Physiology. 2015; 1(1), 1-7.

Cellular and Molecular Pharmacology

Peer-Reviewed Publications

Pedron S, Beverley J, Haffen E, Andrieu P, Steiner H, Van Waes V. Transcranial direct current stimulation produces long-lasting attenuation of cocaine-induced behavioral responses and gene regulation in corticostriatal circuits. Addict. Biol. 2016; doi: 10.1111/adb.12415

Adams T, Rosenkranz JA. Social isolation during postweaning development causes hypoactivity of neurons in the medial nucleus of the male rat amygdala. Neuropsychopharmacology. 2016; 41(7):1929-1940.

Glasgow J, Koshman Y, Samarel AM, Tseng KY, Scrogin K. Myocardial infarction sensitizes medial prefrontal cortex to inhibitory effect of locus coeruleus stimulation in rats. Psychopharmacology. 2016; doi: 10.1007/s00213-016-4305-y

Zhang W, Rosenkranz JA. Effects of repeated stress on age-dependent GABAergic regulation of the lateral nucleus of the amygdala. Neuropsychopharmacology. 2016; doi:10.1038/npp.2016.33.

Bosch OJ, Dabrowska J, Modi ME, et al. Oxytocin in the nucleus accumbens shell reverses CRFR2-evoked passive stress-coping after partner loss in monogamous male prairie voles. Psychoneuroendocrinology. 2016; 64:66-78.

Trossbach SV, Bader V, Hecher L, et al. Misassembly of full-length disrupted-in-schizophrenia 1 protein is linked to altered dopamine homeostasis and behavioral deficits. Mol. Psychiatry; 2016 doi: 10.1038/mp.2015.194.

Mosnaim AD, Hudzik T, Wolf ME. Behavioral effects of [beta]-phenylethylamine and various monomethylated and monohalogenated analogs in mice are mediated by catecholaminergic mechanisms. Am. J. Ther. 2015; 22(6):412-422.

Santiago JA, Potashkin JA. Blood biomarkers associated with cognitive decline in early stage and drug-naive Parkinson's disease patients. PLoS One. 2015; 10(11):e0142582.

Jayasinghe VR, Flores-Barrera E, West AR, Tseng KY. Frequency-dependent corticostriatal disinhibition resulting from chronic dopamine depletion: Role of local striatal cGMP and GABA-AR signaling. Cereb. Cortex. 2015; doi:10.1093/cercor/bhv241.

Jaisinghani S, Rosenkranz JA. Repeated social defeat stress enhances the anxiogenic effect of bright light on operant reward-seeking behavior in rats. Behav. Brain Res. 2015 290:172-179.

Books, Book Chapters, and Review Articles

Caballero A, Granberg R, Tseng KY. Mechanisms contributing to prefrontal cortex maturation during adolescence. Neurosci. Biobehav. Rev. 2016; Doi:10.1016/j.neubiorev.2016.05.013

Caballero A, Tseng KY. GABAergic function as a limiting factor for prefrontal maturation during adolescence. Trends Neurosci. 2016; doi: 10.1016/j.tins.2016.04.010.

Steiner H, Tseng KY, eds. Handbook of Basal Ganglia Structure and Function, 2nd edition, Handbook of Behavioral Neuroscience Series, Vol. 24. London, UK: Academic Press/Elsevier; 2016.

Mosnaim AD, Wolf ME. [Beta]-Phenylethylamine-Class Trace Amines in Neuropsychiatric Disorders: A Brief Historical Perspective, In: Farooqui T, Farooqui A, eds. Trace Amines and Neurological Disorders: Potential Mechanisms and Risk Factors. Elsevier; 2016:285-293.

Steiner H. Psychostimulant-induced gene regulation in striatal circuits, In: Steiner H, Tseng KY, eds. Handbook of Basal Ganglia Structure and Function, Second Edition. Handbook of Behavioral Neuroscience Series, Vol. 24. London, UK: Academic Press/Elsevier; 2016.

Clinical Sciences

Peer-Reviewed Publications

Haas NB, Manola J, Uzzo RG, et al. Adjuvant therapy for high-risk kidney cancer: ECOG-ACRIN E2805, a double-blind, placebo-controlled randomized trial. Lancet 2016; (doi.org/10.1016/S0140-6736(16)00559-6)

Zun L. Care of Psychiatric Patients: The Challenge to Emergency Physicians.
West J Emerg Med. 2016 Mar;17(2):173-6. doi: 10.5811/westjem.2016.1.29648. PubMed PMID: 26973743; PubMed Central PMCID: PMC4786237.

Agarwal N, Rao N, Mekheil M, Tancredi N, Oken J. Safety, efficacy and cost analysis of rivaroxaban versus fondaparinux for thromboprophylaxis after joint replacement at an inpatient rehabilitation facility. J. Pharmacy and Pharmacology. 2015; 3(11), 538-543

Murali AR, Attar BM, Katz A, Kotwal V, Clarke PM. Utility of Platelet Count for Predicting Cirrhosis in Alcoholic Liver Disease: Model for Identifying Cirrhosis in a US Population. J Gen Intern Med. 2015 (8):1112-7.

Andres AM, Pins MR. Papillary thyroid carcinoma with extensive squamous dedifferentiation metastatic to lung: BRAF mutational analysis is a useful tool to rule out tumor to tumor metastases. Virchows Arch 2015; (doi: 10.1007/s00428-015-1875-8)

Books, Book Chapters, and Review Articles

Parrella N. (2016). Metabolic Syndrome. In Domino FJ (Ed.), The 5-Minute Clinical Consult 2017, Philadelphia, PA: Wolters Kluwer. 2016;668-669.

Broutman L. Q&A In: Bates’ Guide to Physical Examination and Health Taking. LWW Health Library. Wolters Kluwer Health; 2015

Pins MR. Male Genitourinary System. In: Gattuso P, Spitz D, Reddy V, Haber M, David O, eds. Differential Diagnosis in Surgical Pathology 3rd ed. New York: W.B. Saunders and Company; 2015.

Zun, L. Managing Psychiatric and altered patients. Emergency Medicine Audiodigest. 2015:32.

Microbiology and Immunology

Peer-Reviewed Publications

Goswami S, Sharma-Walia N. Crosstalk between osteoprotegerin (OPG), fatty acid synthase (FASN) and, cycloxygenase-2 (COX-2) in breast cancer: implications in carcinogenesis. Oncotarget. 2016. doi: 10.18632/oncotarget.9835

Nguyen CB, Kotturi H, Waris G, et al. (Z)-3,5,4'-Trimethoxystilbene Limits Hepatitis C and Cancer Pathophysiology by Blocking Microtubule Dynamics and Cell Cycle Progression. Cancer Res. 2016. pii: canres.2722.2015.

Flaherty S, Reynolds JM. TLR Function in Murine CD4(+) T Lymphocytes and Their Role in Inflammation. Methods Mol Biol. 2016;1390:215-27. doi: 10.1007

Goswami S, Sharma-Walia N. Osteoprotegerin rich tumor microenvironment: implications in breast cancer. Oncotarget. 2016; doi: 10.18632/oncotarget.8658.

Al-Qahtani A, Alkahtani S, Kolli BK, et al. Amino-phthalocyanine-mediated photodynamic inactivation of Leishmania tropica. Antimicrob Ag Chemther. 2016; 60(4):2003-2011.

Dolores J, Tariman JD, Reynolds JM. The Associations and Crosstalk Between Inflammatory and Metabolic Biomarkers in Cancer-Related Fatigue: An Integrative Literature Review. DePaul Online Journal of Nursing Research. 2016.

Veettil MV, Kumar B, Ansari MA, et al. ESCRT-0 component Hrs promotes macropinocytosis of Kaposi’s sarcoma-associated herpesvirus in human microvascular dermal endothelial cells. J Virol. 2016; 28;90(8):3860-72.

McRae S, Iqbal J, Sarkar-Dutta M, et al. The Hepatitis C Virus-induced NLRP3 Inflammasome Activates the Sterol Regulatory Element-binding Protein (SREBP) and Regulates Lipid Metabolism. J Biol Chem. 2016; 12;291(7):3254-67. doi: 10.1074/jbc.M115.694059.

Dambaeva SV, Lee DH, Sung N, et al. Recurrent Pregnancy Loss in Women with Killer Cell Immunoglobulin-Like Receptor KIR2DS1 is Associated with an Increased HLA-C2 Allelic Frequency. Am J Reprod Immunol. 2016; 75(2):94-103. doi: 10.1111/aji.12453.

Katara GK, Kulshrestha A, Jaiswal MK, Pamarthy S, Gilman-Sachs A, Beaman KD. Inhibition of vacuolar ATPase subunit in tumor cells delays tumor growth by decreasing the essential macrophage population in the tumor microenvironment. Oncogene. 2016; 35(8):1058-65. doi: 10.1038/onc.2015.159.

Kulshrestha A, Katara GK, Ginter J, et al. Selective inhibition of tumor cell associated Vacuolar-ATPase 'a2' isoform overcomes cisplatin resistance in ovarian cancer cells. Mol Oncol. 2016; S1574-7891(16)00013-2.

Chandran K, Goswami S, Sharma-Walia N. Implications of a peroxisome proliferator-activated receptor alpha (PPARα) ligand clofibrate in breast cancer. Oncotarget. 2015; doi: 10.18632/oncotarget.6402.

Goswami S, Sharma-Walia N. Osteoprotegerin secreted by inflammatory and invasive breast cancer cells induce aneuploidy, cell proliferation and angiogenesis. BMC Cancer. 2015; 15(1):935. doi: 10.1186/s12885-015-1837-1.

Parvaiz F, Manzoor S, Iqbal J, Sarkar-Dutta M, Imran M, Waris G. Hepatitis C virus NS5A promotes insulin resistance through IRS-1 serine phosphorylation and increased gluconeogenesis. World J. Gastroenterol. 2015; 21:12361-12369.

Ota K, Dambaeva S, Kim MW, et al. 1,25-Dihydroxy-vitamin D3 regulates NK-cell cytotoxicity, cytokine secretion, and degranulation in women with recurrent pregnancy losses. Eur J Immunol. 2015; 45(11):3188-99. doi:10.1002/eji.201545541.

Jaiswal MK, Agrawal V, Katara GK, et al. Male fertility and apoptosis in normal spermatogenesis are regulated by vacuolar-ATPase isoform a2. J Reprod Immunol. 2015; 112:38-45. doi: 10.1016/j.jri.2015.07.003.

Dutta D, Ansari MA, Chandran B. BRCA1-regulated nuclear innate sensing of Herpesviral genome by IFI16 and IFI16’s acetylation is critical for its cytoplasmic trafficking and induction of innate responses. Invited Research Highlights Review. Inflammation and Cell Signaling. 2015; 2: e1076. doi: 10.14800/ics.1076.

Pamarthy S, Jaiswal MK, Kulshreshtha A, Katara GK, Gilman-Sachs A, Beaman KD. The Vacuolar ATPase a2-subunit regulates Notch signaling in triple-negative breast cancer cells. Oncotarget. 2015; 6(33):34206-20. doi: 10.18632/oncotarget.5275.

Ibrahim S, Katara GK, Kulshrestha A, Jaiswal MK, Amin MA, Beaman KD. Breast cancer associated a2 isoform vacuolar ATPase immunomodulates neutrophils: potential role in tumor progression. Oncotarget. 2015; 6(32):33033-45.

Jaiswal MK, Agrawal V, Pamarthy S, et al. Notch Signaling in Inflammation-Induced Preterm Labor. Sci Rep. 2015; 5:15221.

Lun ZR, Wu MS, Chen YF, et al. Visceral Leishmaniasis in China: an Endemic Disease under Control. Clin. Microbial. Rev. 2015; 28 (4), 987-1004.

Chandrasekharan JA, Sharma-Walia N. Lipoxins: nature's way to resolve inflammation. J Inflamm. Res. 2015; 8:181-92. doi: 10.2147/JIR.S90380.

Agrawal V, Jaiswal MK, Pamarthy S, et al. Role of Notch signaling during lipopolysaccharide-induced preterm labor. J Leukoc Biol. 2015; pii: jlb.3HI0515-200RR.

Sheng W, PNG CW, Reynolds JM, Zhang Y. T cell-derived GM-CSF, regulation of expression and function. Immunome Res. 2015; 11:098.

Holthusen K, Talaty P, Everly DN Jr. Regulation of Latent Membrane Protein 1 Signaling through Interaction with Cytoskeletal Proteins. J Virol. 2015; 89(14):7277-90. doi: 10.1128/JVI.00321-15.

Ansari MA, Dutta S, Veettil MV, et al. Herpesvirus genome recognition induced acetylation of nuclear IFI16 Is essential for its cytoplasmic translocation, inflammasome and IFN-β responses. PLoS Pathog. 2015 July;11(7):e1005019. doi: 10.1371/journal.ppat.1005019.

Vahedi S, Chueh FY, Chandran B, Yu CL. Lymphocyte-specific protein tyrosine kinase (Lck) interacts with CR6-interacting factor 1 (CRIF1) in mitochondria to repress oxidative phosphorylation. BMC Cancer. 2015; 15:551.

Books, Book Chapters, and Review Articles

Flaherty S, Reynolds JM. TLR Function in Murine CD4+ T Lymphocytes and their Role in Inflammation. In: Methods of Molecular Biology. Springer: 2016.

Re F. Role of canonical and non-canonical inflammasomes during Burkholderia infection. In: Current Topics in Microbiology and Immunology (CTMI). Inflammasome Signaling and Bacterial Infections. Springer: 2015.

Neuroscience

Peer-Reviewed Publications

Scheyer AF, Loweth JA, Christian DT, et al. AMPA receptor plasticity in accumbens core contributes to incubation of methamphetamine craving. Biological Psychiatry. 2016; doi:10.1016/j.biopsych.2016.04.003

Purgianto A, Loweth JA, Miao JJ, Milovanovic M, Wolf ME. Surface expression of GABAA receptors in the rat nucleus accumbens is increased in early but not late withdrawal from extended-access cocaine self-administration. Brain Research. 2016; 1642: 336-343.

Tan A, Ma W, Vira A, Marwha D, Eliot L. The human hippocampus is not sexually-dimorphic: Meta-analysis of structural MRI volumes. NeuroImage. 2016; 124(Pt A): 350–366.

Gorris R, Fischer J, Erwes KL, et al. Pluripotent stem cell-derived radial glia-like cells as stable intermediate for efficient generation of human oligodendrocytes. Glia. 2015; 63(12): 2152-2167.

Books, Book Chapters, and Review Articles

Wolf ME. Synaptic mechanisms underlying persistent cocaine craving. Nature Reviews Neuroscience. 2016; 17: 351-365.

Shim S, Stutzmann GE. Inhibition of glycogen synthase kinase-3: an emerging target in the treatment of traumatic brain injury. Journal of Neurotrauma. 2016; 10.1089/neu.2015.4177.

Kuhn HG, Eisch AJ, Spalding K, Peterson DA. Detection and phenotypic characterization of adult neurogenesis. Cold Spring Harbor Perspectives in Biology. 2016; 8(3): pii: a025981.

Marr RA. The Amyloid Beta Precursor Protein and Cognitive Function in Alzheimer’s Disease. In: Lazarov O, Tesco G, eds. Genes, Environment and Alzheimer’s disease. Elsevier / Academic Press; 2016: 98-117.

West AR. Nitric Oxide Signaling in the Striatum. In: Steiner H, Tseng KY, eds. Handbook of Basal Ganglia Structure and Function, a Decade of Progress. 2nd Edition. London, UK: Elsevier Inc. Academic Press; 2016.

Physiology and Biophysics

Peer-Reviewed Publications

Candela J, Velmurugan GV, White C. Hydrogen sulfide depletion contributes to microvascular remodeling in obesity. Am J Physiol Heart Circ Physiol. 2016; 310(9):H1071-80.

Gul R, Park DR, Kim D, Kim UH. Nicotinic Acid Adenine Dinucleotide Phosphate (NAADP) and Cyclic ADP-Ribose (cADPR) Mediate Ca2+ Signaling in Cardiac Hypertrophy Induced by β-Adrenergic Stimulation. PloS One. 2016; doi: 10.1371/journal.pone.0149125.

Zhao G, Neely AM, Schwarzer C, et al. N-(3-oxo-acyl) homoserine lactone inhibits tumor growth independent of Bcl-2 proteins. Oncotarget. 2016; 7(5):5924-42.

Leitermann RJ, Rostkowski AB, Urban JH. Neuropeptide Y input to the rat basolateral amygdala complex and modulation by conditioned fear. J Comp Neurol. 2016; doi: 10.1002/cne.23960.

Velmurugan GV, Huang H, Sun H, et al. Depletion of H2S during obesity enhances store-operated Ca2+ entry in adipose tissue macrophages to increase cytokine production. Sci Signal. 2015; 8(407):ra128.

Jia Y, Shah K, Bridges RJ, Bradbury NA. Evidence against resveratrol as a viable therapy for the rescue of defective ∆F508-CFTR. Biochimica et Biophys Acta. 2015; 1850(11):2377-2384.

Butler E, Bradbury NA. Signal dependent ER export of Lemur Tyrosine Kinase 2. BMC Cell Biol. 2015; 11:16-26. doi: 10.1186/s12860-015-0072-6.

Devraj K, Poznanovic S, Spahn C,et al. BACE-1 is expressed in the blood-brain barrier endothelium and becomes upregulated in a mouse model of Alzheimer’s dementia. J Cereb Blood Flow Metab. 2015; pii: 0271678X15606463. PMID: 26661166.

Kim D, Kim I, Wang J, White C, Carroll JL. Hydrogen sulfide and hypoxia-induced changes in TASK activity and intracellular Ca2+ concentration in rat carotid body glomus cells. Respiratory Physiol. and Neurobiol. 2015; 215:30-38.

Ikpa N, Forman R, Garchow K, Sukowski E, Peterson DR. In Vitro Studies on Degradation of Gamma-L-Glutamyl-L-Cysteine and Gamma-L-Glutamyl-D-Cysteine in Blood: Implications for Treatment of Stroke. American Journal of Therapeutics. 2015; 22(4):e97-e106.

Sladek CD, Michelini LC, Stachenfeld NS, Stern JE, Urban JH. Endocrine-Autonomic Linkages. Compr Physiol. 2015; 5(3):1281-323.

Books, Book Chapters, and Review Articles

Dey I, Shah K, Bradbury NA. Natural compounds as therapeutic agents in the treatment cystic fibrosis. J. Genet. Syndr. Gene Ther. 2016; 4(1): 1054-1062.

Bradbury NA. Cystic Fibrosis: A need for personalized medicine. In: Devor, Hamilton, eds. Ion Channels and Transporters of Epithelia in Health and Disease. Springer-Verlag; 2016:773-802.

Shah K, Bradbury NA. Kinase modulation of androgen receptor signaling: implications for prostate cancer. Cancer Cell and Microenvironment. 2015; 2(4): e1023.

Neil A. Bradbury. Cystic Fibrosis. In: Bradshaw RA, Stahl PD, eds. Encyclopedia of Cell Biology, Vol 1, Waltham, MA: Academic Press; 2015:252-262.

Dr. William M. Scholl College of Podiatric Medicine

Basic Biomedical Sciences

Peer-Reviewed Publications

Leontovich AA, Intine RV, Sarras MP Jr. Epigenetic studies point to DNA replication/repair genes as a basis for the heritable nature of long term complications in diabetes. J Diabetes Res. 2016; Vol. 2016: 1-10. doi: 10.1155/2016/2860780

Sarras MP Jr, Leontovich AA, Intine RV. Use of zebrafish as a model to investigate the role of epigenetics in propagating the secondary complications observed in diabetes mellitus. Comp Biochem Physiol C Toxicol Pharmacol. 2015; 178: 3-7. doi: 10.1016/j.cbpc.2015.07.001

Books, Book Chapters, and Review Articles

Sarras MP Jr, Leontovich AA, Intine RV. A potential gDNA methylation epigenetic mechanism to explain the long term complications of type 1 and 2 diabetes. In MOJ Anatomy & Physiology, ed. MOJ Anat and Physiol 2016; 2(3): 49-52. doi: 10.15406/mojap.2016.02.00049

Podiatric Surgery and Applied Biomechanics

Peer-Reviewed Publications

Crews RT, Schneider KL, Yalla SV, Reeves ND, Vileikyte L. Physiological and psychological challenges of increasing physical activity and exercise in patients at risk of diabetic foot ulcers: a critical review. Diabetes Metab Res Rev. 2016; doi: 10.1002/dmrr.2817.

Pater ML, Rosenblatt NJ, Grabiner MD. Knee osteoarthritis negatively affects recovery step following large forward-directed postural perturbations. J Biomech. 2016; 49(7): 1128-33. doi: 10.1016/j.jbiomech.2016.02.048

Wrobel J, Fleischer A, Matzkin-Bridger J, et al. Physical examination variables predict response to conservative treatment of non-chronic plantar fasciitis: Secondary analysis of a randomized placebo controlled footwear study. PM&R. 2016; 8(5): 436-44. doi:10.1016/j.pmrj.2015.09.011

Kirsner R, Bohn G, Driver V, et al. Human acellular dermal wound matrix: evidence and experience. Int Wound J. 2015; 12(6): 646-54. doi: 10.1111/iwj.12185

Grady J, Trotter K, Ruff J, Miller S. Radiographic investigation of the absolute and relative first metatarsal lengths in the asymptomatic foot. J Am Podiatr Med Assoc. 2015; 105(6): 478-483. doi: 10.7547/13-099.1

Fleischer AE, Albright RH, Crews RT, Kelil T, Wrobel J. Prognostic value of diagnostic sonography in patients with plantar fasciitis. J Ultrasound Med. 2015; 34(10): 1729-1735. doi: 10.7863/ultra.15.14.10062

Rosenblatt NJ, Latash ML, Hurt CP, Grabiner MD. Challenging gait leads to stronger lower-limb kinematic synergies: the effects of walking within a more narrow pathway. Neurosci Lett. 2015; 600: 110-4. doi: 10.1016/j.neulet.2015.05.039

Wrobel JS, Fleischer AE, Crews RT, Jarrett B, Najafi B. A randomized controlled trial of custom foot orthoses for the treatment of plantar heel pain: a return to spontaneous physical activity. J Am Podiatr Med Assoc. 2015; 105(4): 281-94. doi: 10.7547/13-122.1

Books, Book Chapters, and Review Articles

Wu SC, Armstrong DG. Offloading the diabetic foot wound. In: Amstrong D, Lavery L, ed. Clinical Care of the Diabetic Foot, 3rd ed. Alexandria, MD: American Diabetes Association; 2015

College of Health Professions

Interprofessional Healthcare Studies

Peer-Reviewed Publications

Thuente L, Batteson TJ. Teaching collaboration competencies to healthcare provider students through simulation. J Allied Health. 2016; 45(2): 147-151

Comerford J, Batteson T, Tormey R. Academic buoyancy in second level schools: Insights From Ireland. Procedia Soc Behav Sci. 2015; 197: 98-103. doi:10.1016/j.sbspro.2015.07.061

Books, Book Chapters, and Review Articles

Myser C. Building reflective learning communities of multigenerational ‘ethics peer mentors’ to help students recognize and manage ethics challenges. In: Peterkin and Brett-MacLean, eds. Keeping Reflection Fresh: Top Educators Share Their Innovations in Health Professional Education, Literature and Medicine Series. Kent, OH: Kent State University Press; 2015; 266-270.

Nutrition

Books, Book Chapters, and Review Articles

Insel P, Ross D, McMahon K, Bernstein M. Nutrition. 6th ed. Burlington, MA: Jones & Bartlett Learning; 2016.

Pathologists’ Assistant

Peer-Reviewed Publications

Vitale J. Form versus function: what does and does not constitute an interprofessional team. HIP. 2016; 3(1). doi:10.7710/2159-1253.1099

Physical Therapy

Peer-Reviewed Publications

Alibiglou L, Videnovic A, Planetta PJ, Vailancourt DE, MacKinnon CD. Subliminal gait initiation deficits in REM sleep behavior disorder: a harbinger of freezing of gait? Mov Disord [serial online]. June 2, 2016; doi: 10.1002/mds.26665

Bell K, DiLiberto FE. Segmental forefoot kinematics could influence risk of ulceration. Lower Extremity Review. 2016.

Nawoczenski DA, DiLiberto FE, Cantor M, Tome J, DiGiovanni B. Ankle power and endurance outcomes following isolated gastrocnemius recession for Achilles tendinopathy. J Foot Ankle Surg. 2016; doi: 10.1177/1071100716638128

DiLiberto FE, Tome J, Baumhauer JF, Houck J, Nawoczenski DA. Individual metatarsal and forefoot kinematics during walking in people with diabetes mellitus and peripheral neuropathy. Gait Posture. 2015; 42(4): 435-441. doi: 10/1016/j.gaitpost.2015.07.012

DiLiberto FE, Tome J, Baumhauer JF, Quinn JR, Houck J, Nawoczenski DA. Multi-joint foot kinetics during walking in people with diabetes mellitus and peripheral neuropathy. J Biomech. 2015; 48(13): 3679-3684. doi: 10.1016/j.jbiomech.2015.08.020

Books, Book Chapters, and Review Articles

Frownfelter D. Planning transition to adult life. In: Rahlin M, ed. Physical Therapy for Children with Cerebral Palsy: An evidence-Based Approach. Thorofare, NJ: SLACK Incorporated; 2016.

Rahlin M. Physical Therapy for Children with Cerebral Palsy: An Evidence-Based Approach. Thorofare, NJ: SLACK Incorporated; 2016.

Rahlin M, Henderson R. Pain assessment and management. In: Rahlin M, ed. Physical Therapy for Children with Cerebral Palsy: An evidence-Based Approach. Thorofare, NJ: SLACK Incorporated; 2016.

Rahlin M, Rheault W. The interdisciplinary team and effective interprofessional collaboration in health care. In: Rahlin M, ed. Physical Therapy for Children with Cerebral Palsy: An evidence-Based Approach. Thorofare, NJ: SLACK Incorporated; 2016: 103-110.

Physicians’ Assistant

Peer-Reviewed Publications

Knott P, Sturm P, Lonner B, et al. Multicenter comparison of 3D spinal measurements using surface topography to those from conventional radiography. Spine Deform. 2016; 4: 98-103. doi: 10.1016/j.jspd.2015.08.008

Hegmann T, Roscoe M, Statler M. Reliability and validity of PAEA End of Rotation™ examination scores for predicting performance on the Physician Assistant National Certification Examination. J Physician Assist Educ. 2015; 26(4): 187-192. doi: 10.1097/JPA.0000000000000044

Draus C, Moravec D, Kopiec A, Knott P. Comparison of barefoot vs. shod gait on spinal dynamics using DIERS Formetric 4D and DIERS Pedoscan Systems. Int J Ther Rehabil. 2015; 3: 70-76. doi: 10.4236/ojtr.2015.33010

Psychology

Peer-Reviewed Publications

DiGangi JA, Goddard AJ, Miller SA, Leon G, Jason LA. Differences in PTSD symptomatology among latinos with childhood and adult trauma: the moderating effect of acculturation. HSOA J Addict Neuropharmacol. 2016; 3: 009.

Pera-Guardiola V, Contreras-Rodriguez O, Batalla I, et al. Brain structural correlates of emotion recognition in psychopaths. PLoS One. 2016; 11(5): e0149807. doi:10.1371/journal.pone.0149807

Leon SC, Miller SA, Stoner AM, Fuller A, Rolnik AM. Change trajectories: children's patterns of improvement in acute-stay inpatient care. J Behav Health Serv Res. 2016; 43(2): 233-245. doi: 10.1007/s11414-014-9432-9

Nguyen E, Bugno L, Kandah C, et al. Is there a good app for that? evaluating mHealth apps for strategies that promote pediatric medication adherence. Telemed J E Health. 2016; doi: 10.1089/tmj.2015.0211

Reed-Knight B, Lee J, Greenley RN, Lewis JD, Blount RL. Disease activity does not explain it all: how internalizing symptoms and caregiver depressive symptoms relate to health-related quality of life among youth with inflammatory bowel disease. Inflamm Bowel Dis. 2016; 22(4): 963-967. doi: 10.1097/MIB.0000000000000686

Schneider K, Coons M, McFadden H, et al. Mechanisms of change in diet and activity in the make better choices 1 trial. Health Psychol. 2016; 35(7): 723-32. doi: 10.1037/hea0000333

Wojtowicz AA, Plevinsky J, Poulopoulos N, Schurman JV, Greenley RN. Examining predictors of health care utilization in youth with inflammatory bowel disease. Eur J Gastroenterol Hepatol. 2016; 28(4): 469-474. doi: 10.1097/MEG.0000000000000540

DeCator DD, Carter JS, Schneider KL. Family meals, obesogenic factors, and depressive symptoms in youth. Ment Health Phys Act. 2016; 10: 1-3. doi:10.1016/j.mhpa.2016.01.002

Hanna R, Shalvoy A, Cullum M, et al. Cognitive function in individuals with psychosis: moderation by adolescent cannabis use. Schizophr Bull. 2016; pii: sbw030.

Hinrich A, Jodelka F, Brutman D, et al. Therapeutic correction of deregulated ApoER2 splicing in Alzheimer’s disease using antisense oligonucleotides. EMBO Mol Med. 2016; 8(4): 328-45. doi: 10.15252/emmm.201505846

Walter J, Kahn SA, Noe J, Schurman JV, Miller SA, Greenley RN. Feeling fine: anxiety and depressive symptoms in youth with established IBD. Inflamm Bowel Dis. 2016; 22(2): 402-408. doi: 10.1097/MIB.0000000000000657

Hochberger W, Hill S, Nelson C, et al. Unitary construct of generalized cognitive ability underlying BACS performance across psychotic disorders and in their first-degree relatives. Schizophr Res. 2016; 170(1): 156-61. doi: 10.1016/j.schres

Goldner J, Richards M, Quimby D, et al. Relations of parenting to adolescent externalizing and internalizing distress moderated by perception of neighborhood danger. J Clin Child Adolesc Psychol. 2016; 45(2): 141-54. doi: 10.1080/15374416.2014.958838

Schneider K, Panza P, Handschin B, et al. Feasibility of pairing behavioral activation with exercise for women with type 2 diabetes and depression: the get it study pilot randomized controlled trial. Behav Ther. 2016; 47(2): 198-212. doi: 10.1016/j.beth.2015.10.005

Greenley R, Gumidyala A, Nguyen E, et al. Can you teach a teen new tricks? problem solving skills training improves oral medication adherence in pediatric IBD patients participating in a randomized trial. Inflamm Bowel Dis. 2015; 21(11): 2649-57. doi: 10.1097/MIB.0000000000000530

Hemphälä M, Kosson DS, Westerman J, Hodgins S. Stability and predictors of psychopathic traits from mid-adolescence through early adulthood among men and women treated for substance misuse in adolescence. Scand J Psychol. 2015; 56: 649-658. doi: 10.1111/sjop.12257

Garcia-Ramos C, Jackson D, Lin J, et al. Cognition and brain development in children with benign epilepsy with centrotemporal spikes. Epilepsia. 2015; 56(10): 1615-22. doi: 10.1111/epi.13125

Pagoto S, Waring M, Schneider K, et al. Twitter-delivered behavioral weight loss interventions: a pilot series. JMIR Res Protoc. 2015; Oct 23;4(4): e123. doi: 10.2196/resprot.4864

Vitale DS, Greenley RN, Lerner DG, Mavis AM, Werlin SL. Adherence to infliximab treatment in a pediatric inflammatory bowel disease cohort. J Pediatr Gastroenterol Nutr. 2015; 61(4): 408-10. doi: 10.1097/MPG.0000000000000817

Lemon S, Valentine-Goins K, Schneider K, et al. Municipal officials participation in built environment policy development in the united states. Am J Health Promot. 2015; 30(1): 42-49. doi: 10.4278/ajhp.131021-QUAN-536

Segal NL, Li NP, Graham JL, Miller SA. Do parents favor their adoptive or biological children? predictions from kin selection and compensatory models. Evol Hum Behav. 2015; 36(5): 379-388. doi: 10.1016/j.evolhumbehav.2015.03.001

Sierles FE, Kessler K, Mintz M, et al. Changes in medical students’ exposure to and attitudes about drug company interactions from 2003 to 2012: a multi-institutional follow-up survey. Acad Med. 2015; 90(8): 1137-46. doi: 10.1097/ACM.0000000000000686

Pratt S, Jerome G, Schneider K, et al. Position statement from the society of behavioral medicine and the american college of sports medicine: increase united states health plan coverage for exercise programming in community mental health programs for people with serious mental illness. Transl Behav Med. 2015.

Books, Book Chapters, and Review Articles

Kosson DS, Gacono C, Klipfel KM, Bodholdt R. Understanding and assessing psychopathy: interpersonal aspects and clinical interviewing. In: Gacono, CB ed. The Clinical and Forensic Assessment of Psychopathy. New York, NY: Routledge, Taylor & Francis Group; 2016; 2nd ed.

Kosson DS, Vitacco MJ, Swogger MT, Steuerwald BL. Emotional experiences of the psychopath. In: Gacono, CB ed. The Clinical and Forensic Assessment of Psychopathy. New York, NY: Routledge, Taylor & Francis Group; 2016; 2nd ed.

College of Pharmacy

Peer-Reviewed Publications

Patel TS, Cottreau JM, Hirsch EB, Tam VH. Impact of hyperglycemia on outcomes of patients with pseudomonas aeruginosa bacteremia. Diagn Microbiol Infect Dis. 2016; 84(2): 155-158. doi: 10.1016/j.diagmicrobio.2015.10.024

Shim S, Shuman M, Duncan E. An emerging role of cGMP in the treatment of schizophrenia. Schizophr Res. 2016; 170(1): 226-231. doi: 10.1016/j.schres.2015.11.015

Wall A, Aljets A, Ellis S, et al. White paper on pharmacy admissions: developing a diverse work force to meet the health-care needs of an increasingly diverse society. Amer J Pharm Educ. 2015; 79(7): S7. doi: 10.5688/ajpe797S7

Patil SA, Patil R, Keri RS, Budagumpi S, Balakrishna GR, Tacke M. N-Heterocyclic carbene metal complexes as bioorganometallic antimicrobial and anticancer drugs. Future Med Chem. 2015; 7(10): 1305-1333. doi: 10.4155/fmc.15.61

Books, Book Chapters, and Review Articles

Cottreau JM, Barr VO. A review of antiviral and antifungal use and safety during pregnancy. Pharmacotherapy, 2016; June; 36(6): 668-678. doi: 10.1002/phar.1764. Epub 2016 May 3.

Kane S. Comment: correlation of free and total phenytoin serum concentrations in critically ill patients. Ann Pharmacother. 2016; June; 50(6): 519. doi: 10.1177/1060028016644467. Epub 2016 Apr 15.

Patil SA, Patil SA, Patil R, Hashizume R. Imidazoquinolines: recent developments in anticancer activity. Mini Rev Med Chem, 2016; 16(4): 309-322.

Mody VV, Singh AN, Deshmukh R, Shah S. Thyroid hormones, iodine and iodides, and antithyroid drugs. In: Ray SD, ed. Side Effects of Drugs Annual. Vol 37. Amsterdam, Neth: Elsevier 2015; Chapter 40: 513-519.

Angelo L. APhA's Immunization Handbook, 3rd Edition. Washington, DC: American Pharmacists Association; 2015.

Sponsored Research Awards by Department

Chicago Medical School

PI Name Agency Title Project Dates Funds - Current Year

Biochemistry and Molecular Biology

Correll, Carl University of Texas-Austin Biogenesis of the Small Ribosomal Subunit in Eukaryotes 03/01/2016 - 02/28/2018 79,265.00
Lu, Min National Institute Of Health Structural mechanisms of multidrug extrusion by the MATE antiporters 09/01/2015 - 08/31/2019 314,856.00
Mueller, David National Institute Of Health Structure and function of the ATP synthase 07/01/2015 - 06/30/2016 318,095.00
Oh, Kyoung Joon National Institute Of Health BAX/BAK-Mediated Mitochondrial Outer Membrane Permeabilization in Apoptosis 02/01/2016 - 01/31/2017 293,709.00
      Department Total: 1,005,925.00

Cell Biology and Anatomy

Frost, William National Science Foundation Stimulus-Induced Neural Networks 08/01/2015 - 07/31/2017 193,285.00
Hastings, Michelle National Institute Of Health Correction of Hearing and Vestibular Defects in a Mouse Model for Deafness 02/01/2016 - 01/31/2017 319,388.00
Hastings, Michelle ISIS Pharmaceuticals In vitro and in vivo analysis of the effect of antisense oligonucleotides that target CLN3 exon 6 and exon 9 splicing 05/27/2016 - 05/26/2017 49,999.00
Hastings, Michelle Louisiana State Univ-Fighting Blindness An Antisense-Oligonucleotide Treatment for Retinitis Pigmentosa in Usher Syndrome 07/18/2015 - 07/17/2016 107,470.00
Hastings, Michelle Batten Disease Support and Research Assoc Antisense Oligonucleotides for the Treatment of Juvenile Neuronal Ceroid Lipofuscinosis 10/01/2015 - 09/30/2016 50,000.00
Hastings, Michelle Batten Disease Support and Research Assoc Stop Codon Readthrough and Nonsense Suppression for the Treatment of Infantile and Late-Infantile Neuronal Ceroid Lipofuscinosis 10/01/2015 - 09/30/2016 25,000.00
Hastings, Michelle Sanford Research Searching for an Effective Treatment for a CLN6 Batten Disease 10/01/2015 - 09/30/2016 37,443.00
Kim, Hongkyun National Institutes of Health Alcohol-induced muscle damage in C. elegans 03/10/2016 - 02/28/2018 224,250.00
      Department Total: 1,006,835.00

Cellular and Molecular Pharmacology

Dabrowska, Joanna National Institute Of Health CRF-oxytocin interaction in the regulation of stress and affect 04/01/2016 - 03/31/2017 248,999.00
Potashkin, Judith National Institute Of Health Blood RNA biomarkers of Parkinson's disease and progressive supranuclear palsy 06/01/2016 - 05/31/2018 321,256.00
Rosenkranz, Jeremy
Multiple Principal Investigator
National Institute Of Health Sex differences in amygdala function 12/01/2015 - 11/30/2018 230,978.00
Rosenkranz, Jeremy National Institute Of Health Effects of chronic stress on amygdala physiology 06/01/2016 - 05/31/2018 351,000.00
Rosenkranz, Jeremy National Institute Of Health Effects of repeated stress on amygdala function during adolescence 02/16/2016 - 01/31/2020 273,000.00
Tseng, Kuei-Yuan
Multiple Principal Investigator
National Institute Of Health Gene Therapy Targeting Striatal cGMP signaling in experimental parkinsonism 07/01/2015 - 06/30/2017 123,234.00
Tseng, Kuei-Yuan National Institute Of Health Afferent Regulation of Prefrontal Maturation during Adolescence 02/15/2016 - 12/31/2020 390,000.00
Tseng, Kuei-Yuan
Rosenkranz, Jeremy (Co-Investigator)
National Institute Of Health Adolescent Maturation of the Prefrontal Cortex: Modulation by Cannabinoids 09/01/2015 - 06/30/2020 390,000.00
      Department Total: 2,328,467.00

Microbiology and Immunology

Chandran, Bala National Institute Of Health KSHV interactions with host inflammasome components 02/01/2016 - 01/31/2019 320,588.00
Chandran, Bala
Veettil Mohanan (Co-Investigator)
National Institute Of Health Early events of in vitro KSHV infection 04/01/2016 - 03/31/2017 320,588.00
Everly, David American Cancer Society Regulation of Signaling and Transformation by LMP1 of EBV 07/01/2015 - 06/30/2016 180,000.00
Everly, David
Joseph Reynolds (Co-Investigator)
National Multiple Sclerosis Society Association between viral load and encephalitogenic T cell activation in Multiple Sclerosis 10/01/2015 - 09/30/2016 110,000.00
Re, Fabio National Institute Of Health Role of neutrophils and elastase in melioidosis 05/01/2016 - 04/30/2020 387,999.00
Re, Fabio Emory University Modulation of Host Responses by Mycobacterium tuberculosis 04/01/2016 - 02/28/2017 32,733.00
Reynolds, Joseph American Lung Association Critical roles of IL-17 family member cytokines in regulating pulmonary inflammation 07/01/2015 - 06/30/2017 40,000.00
Reynolds, Joseph National Multiple Sclerosis Society Novel Role of Endogenous biglycan in promoting IL-17 mediated autoimmune inflammation 10/01/2015 - 09/30/2016 44,000.00
Waris, Gulam National Institute Of Health Hepatitis C virus-induced inflammasome and lipid metabolism 05/15/2016 - 04/30/2021 351,000.00
      Department Total: 1,786,908.00

Neuroscience

Christian, Daniel National Institute Of Health Plasticity in nucleus accumbens spines during incubation of cocaine craving 04/20/2016 - 04/19/2017 56,118.00
Eliot, Lise Snite Foundation Meta-analysis of Gender Difference in the Human Amygdala 06/01/2016 - 05/31/2019 10,000.00
Loweth, Jessica National Institute Of Health Do Cocaine and Chronic Stress Converge in the Basolateral Amygdala? 07/01/2015 - 06/30/2017 126,415.00
Marr, Robert
Multiple Principal Investigator
National Institute Of Health Validating novel ryanodine receptor-targeted compounds for AD therapeutics 04/01/2016 - 03/31/2017 97,500.00
Peterson, Daniel University of Chicago Diabetes Research and Training Center Defining stem cell populations in diabetic skin 08/01/2015 - 01/31/2016 25,000.00
Stefanik, Michael National Institutes of Health Protein translation and the incubation of cocaine craving 07/12/2015 - 07/11/2018 50,690.00
Stutzmann, Grace
Multiple Principal Investigator
National Institute Of Health Validating novel ryanodine receptor-targeted compounds for AD therapeutics 04/01/2016 - 03/31/2017 97,500.00
Stutzmann, Grace
Multiple Principal Investigator
Alzheimer's Association Intracellular Ca2+channels as a therapeutic target for AD drug discovery 10/01/2015 - 09/30/2018 51,293.00
Stutzmann, Grace
Multiple Principal Investigator
Alzheimer's Drug Discovery Foundation Drug Development and Optimization of Compounds Stabilizing Ryanodine Calcium Channels for AD 01/01/2016 - 12/31/2016 144,680.00
West, Anthony
Multiple Principal Investigator
National Institute Of Health Gene Therapy Targeting Striatal cGMP signaling in experimental parkinsonism 07/01/2015 - 06/30/2017 123,234.00
West, Anthony lundbeck Research USA, Inc. Impact of Vortioxetine on synaptic integration in prefrontal-striatal circuits 02/01/2016 - 01/31/2016 53,263.00
Wolf, Marina;
Tseng, Kuei-Yuan (Co-Investigator)
National Institute Of Health Synaptic mechanisms maintaining persistent cocaine craving. 05/01/2016 - 05/31/2019 363,268.00
Wolf, Marina University of Pittsburgh Fed Sub-NIH Homeostatic Regulation and Dysregulation in Cocaine Craving 05/01/2016 - 04/30/2018 70,498.00
      Department Total: 1,269,459.00

Physiology and Biophysics

Dimitrov, Eugene National Institutes of Health Amygdala and Pain-Associated Mood Disorders 12/01/2015 - 11/30/2019 390,000.00
Kim, Donghee National Institute Of Health Mechanism of oxygen sensing by chemoreceptor cells 07/01/2015 - 06/30/2017 342,411.00
Peterson, Darryl
Gazmuri, Raul (Co-Investigator)
James R. & Helen D. Russell Institute for Research Prevention of Oxidative Injury to the Neonatal Heart 06/01/2016 - 12/31/2017 24,999.00
Sackin, Henry National Institute Of Health Molecular Cloning of Epithelial K Channels 06/01/2016 - 05/31/2018 351,000.00
Urban, Janice
Multiple Principal Investigator
National Institute Of Health Sex differences in amygdala function 12/01/2015 - 11/30/2018 155,273.00
      Department Total: 1,263,683.00

Resuscitation Institute

Gazmuri, Raul Zoll Medical Corp AMSA to Guide Shock Delivery in a Swine Model of Ventricular Fibrillation and Closed Chest Resuscitation 05/17/2016 - 05/16/2017 133,229.00
      Department Total: 133,229.00

College of Health Professions

PI Name Agency Title Project Dates Funds - Current Year

College of Health Professions

Bridges, Diane Association for Prevention Teaching and Research Student Run Inter-professional Free Clinic at RFUMS 07/01/2015 - 07/31/2016 4,000.00
      Department Total: 4,000.00

Nurse Anesthesia

Larson, Sandra Health Resources and Services Administration Rosalind Franklin University Nurse Anesthesia Program Student Support Initiative 07/01/2015 - 06/30/2016 25,036.00
      Department Total: 25,036.00

Psychology

Seidenberg, Michael University of Wisconsin-Madison (NIH) Neuropsychological Progression of New Onset Epilepsy 08/01/2015 - 07/31/2016 17,020.00
      Department Total: 17,020.00

College of Pharmacy

PI Name Agency Title Project Dates Funds - Current Year

Pharmaceutical Sciences

Buolamwini, John Texas Tech UniversityHSC-SubFed Novel Small Molecule MDM2 Inhibitors for Pancreatic Cancer Therapy 03/01/2016 - 02/28/2019 66,789.00
Buolamwini, John
Multiple Principal Investigator
Alzheimer's Association Intracellular Ca2+channels as a therapeutic target for AD drug discovery 10/01/2015 - 09/30/2018 48,407.00
Buolamwini, John
Multiple Principal Investigator
Alzheimer's Drug Discovery Foundation Drug development and optimization of compounds stabilizing ryanodine calcium channels for AD 01/01/2016 - 12/31/2016 113,262.00
Rynn, Kevin National Assoc of Chain Drug Stores Community Pharmacy Residency Expansion Project 07/01/2015 - 06/30/2016 10,000.00
Shanahan, Kristy American Society for Clinical Laboratory Science Blood Biomarkers to Assess Suicide Risk 08/03/2015 - 07/31/2016 5,000.00
Walters, D.E. Purdue University (NIH) Design and Synthesis of Nonpeptide Inhibitors of HIV Protease 09/01/2015 - 08/31/2016 14,400.00
      Department Total: 257,858.00

Dr. William M. Scholl College of Podiatric Medicine

PI Name Agency Title Project Dates Funds - Current Year

CLEAR

Joseph, Robert Skin and Wound Allograft Institute A Multicenter, Randomized, Controlled, Open-Labeled Trial to Assess the Clinical Effectiveness of DermACELL, Conventional Care Wound Management, and GraftJacket in subjects with Chronic Wounds in the 07/17/2015 - 01/16/2016 8,338.00
Lin, Fang American Podiatric Medical Students' Association Is Foot Length Change During Stance Phase Decreased in Individuals with Diabetes? 08/25/2015 - 05/31/2016 1,000.00
Rosenblatt, Noah National Institute Of Health A modifiable Biomechanical Explanation for Obesity-Related Falls by Older Adults 08/05/2015 - 07/31/2018 80,356.00
Yalla, Sai
Ryan Crews (Co-Investigator)
Weil Foot and Ankle Research Foundation Effectiveness of a novel elastic ankle exoskeleton brace for the treatment of plantar heel pain 08/01/2015 - 04/30/2016 6,966.00
Yalla, Sai American Podiatric Medical Students' Association Does Microprocessor based Prosthesis improve Balance and Activity patterns in Above Knee Amputees 08/25/2015 - 05/31/2016 1,000.00
      Department Total: 97,660.00

SCPM Surgery

Wu, Stephanie National Institute Of Health Summer Research Fellowship Program for Podiatric Medical Students 05/01/2016 - 04/30/2019 48,639.00
Wu, Stephanie Celgene Corporation A Phase I, Multicenter, Open-Label, Dose-Escalation Study to Evaluate the Safety and Efficacy of Intramuscular Injection of Human Placenta-Derived Cells (PDA-002) in subjects with Peripheral Arterial 09/04/2015 - 09/03/2015 3,119.00
Wu, Stephanie Dipexium Pharmaceuticals Inc A Randomized, Double Blind Multicenter Superiority Placebo Controlled Phase 3 Study of Pexiganan Cream 0.8% Applied Twice Daily for 14 days in the Treatment of Adults with Mild Infections of Diabetic 08/20/2015 - 08/19/2015 29,285.00
Wu, Stephanie Celgene Corporation A Phase 2 Multicenter, Randomized, Doubleblind, Placebo-Controlled, Dose Range Finding Study tp Evaluate the Efficacy and Safety of Intramuscular Injection of Huma Placenta-Derived Cells (PDA-002) in 12/19/2015 - 12/18/2016 3,720.00
Wu, Stephanie Smith & Nephew A Prospective, Randomized, Comparative Effectiveness Study of a Single-Use, Negative Pressure Wound Therapy System (PICO) versus a Traditional Negative Pressure Wound Therapy System (tNPWT) in the... 01/06/2016 - 12/31/2017 14,866.00
Wu, Stephanie Amniox, Inc A Multi-center, Randomized, Controlled Trial of Non-healing Diabetic Fppt Ulcers (DFU) Treated with Standard of Care with or without Cryopreserved Umbilical Cord Allograft (NEOX CORD 1KTM) 03/09/2016 - 02/28/2018 8,000.00
      Department Total: 107,629.00

Community and Education Grants

Project Manager/ Faculty Lead Sponsor Purpose Project Period Amount
Gianfortune, Philip VNA Foundation Scholl Podiatric Care for the Underserved Program 9/1/2015 - 8/31/2016 18,000.00
Mavrolas, Cathy; Radke, Jason Healthcare Foundation of Northern Lake County Healthy Families Program 5/16/2016 - 5/15/2016 40,000.00
Neimeyer, Bruce Telligen Community Foundation Health Professions Education Consortium 1/1/2016 - 12/31/2016 50,000.00
Pabon, Amanda Healthcare Foundation of Northern Lake County CHW Partnership 11/24/2015 - 11/23/2016 60,000.00
Rasgado-Flores, Hector AbbVie INSPIRE 12/11/2015 - 12/10/2016 66,000.00
Smith, Michael Grace Bersted Foundation (Bank of America) Community Care Connection 1/1/2016 - 12/31/2016 15,000.00
Smith, Michael IOMC/Blue Cross Blue Shield Foundation Community Care Connection 1/1/2016 - 12/31/2016 22,800.00
Wenzel, Alyssa Society of Infectious Diseases Pharmacists Merck Infectious Diseases Pharmacotherapy Residency/Fellow Award for 2016 - 2017. 7/1/2015 - 6/30/2016 60,000.00
  Dr. Scholl Foundation Dr. William M. Scholl College of Podiatric Medicine Scholarships 12/31/2015 - 12/30/2016 125,000.00
  Gorter Family Foundation Summer Research Training Program 1/1/2016 - 12/31/2016 15,000.00
  Grace Elizabeth Groner Scholarship Foundation College of Pharmacy - Scholarships 7/1/2015 - 6/30/2016 40,000.00
  Healthcare Foundation of Northern Lake County Interprofessional Healthcare Scholarship Program 5/16/2016 - 5/15/2016 70,000.00
      Total: 584,800.00

Drug Discovery Screening Research

FY2016 Drug Discovery Screening Research Revenue was $1.9 million.