Center for Proteomics and Molecular Therapeutics
We foster interdisciplinary collaborations to translate protein-based research into diagnostics, prognostics, and treatments by unveiling the molecular complexities of diseases and discovering disease-specific biomarkers.
In this section
In this section
Marc Glucksman, PhD
Director, Center for Proteomics and Molecular Therapeutics
- Marc Glucksman – Center Director
- The structural neurobiology of processing enzymes.
- Use of a proteomics-based approach to identify Alzheimer’s disease-specific biomarkers.
- Enzymes and neuropeptide substrates of several reactions involved in the normal and disease states of neurobiological, aging and reproductive processes
- Proteomic approaches are utilized in projects to identify markers and assess structure-function relationships for diagnostics, risk factors and targets for treatment of Alzheimer's disease, schizophrenia and endocrine cancers (e.g. prostate)
- Carl Correll
- Identify and investigate the function of proteins that are essential for ribosome biogenesis - a vital cellular process that is emerging as an unexplored target for cancer treatment.
- Lisa Ebihara
- The biophysical and pharmacological properties of gap junctional channels in the lens of the eye and other tissues.
- Adrian Gross
- The structure and functional mechanism of potassium channels.
- Ronald Kaplan
- Discovery of high-affinity inhibitors and determination of the three-dimensional structure of the INDY (I'm Not Dead Yet) transporter, a carrier which may play a role in obesity, a major risk factor for adult-onset diabetes.
- The structure and functional mechanism of the mitochondrial and plasma membrane citrate transporters
- Donghee Kim
- The role of ion channels in the modulation of cell excitability at rest and in response to various stimuli.
- Min Lu
- The structure and functional mechanism of the Multidrug and Toxin Extrusion transporter.
- Kyoung Joon Oh
- The structure and functional mechanism of key proteins of apoptosis.
- Henry Sackin
- The structure and functional mechanism of potassium channels.