Center for Neurobiology of Stress Resilience and Psychiatric Disorders Diseases

Addiction

• Jeremy Amiel Rosenkranz
  
  • Munshi S, Rosenkranz JA, Caccamise A, Wolf ME, Corbett CM, Loweth JA. Cocaine and chronic stress exposure produce an additive increase in neuronal activity in the basolateral amygdala.  Addict Biol. 2019 Nov 21:e12848. doi: 10.1111/adb.12848.
  • Glynn RM, Rosenkranz JA, Wolf ME, Caccamise A, Shroff F, Smith AB, Loweth JA. Repeated restraint stress exposure during early withdrawal accelerates incubation of cue-induced cocaine craving. Addict Biol. 2018 23:80-89.

Anxiety

• Joanna Dabrowska
  • Marvar PJ, Andero R, Hurlemann R, Lago TR, Zelikowsky M, Dabrowska J. Limbic Neuropeptidergic Modulators of Emotion and Their Therapeutic Potential for Anxiety and Post-Traumatic Stress Disorder. J Neurosci. 2021 Feb 3;41(5):901-910. doi: 10.1523/JNEUROSCI.1647-20.2020. Epub 2021 Jan 20. PMID: 33472824; PMCID: PMC7880296.
  • Martinon D, Lis P, Roman AN, Tornesi P, Applebey SV, Buechner G, Olivera V, Dabrowska J. Oxytocin receptors in the dorsolateral bed nucleus of the stria terminalis (BNST) bias fear learning toward temporally predictable cued fear. Transl Psychiatry. 2019 Apr 18;9(1):140. doi: 10.1038/s41398-019-0474-x.
  • Janeček M, Dabrowska J. Oxytocin facilitates adaptive fear and attenuates anxiety responses in animal models and human studies-potential interaction with the corticotropin-releasing factor (CRF) system in the bed nucleus of the stria terminalis (BNST). Cell Tissue Res. 2019 Jan;375(1):143-172. doi: 10.1007/s00441-018-2889-8. Review.
  • Martinon D, Dabrowska J. Corticotropin-Releasing Factor Receptors Modulate Oxytocin Release in the Dorsolateral Bed Nucleus of the Stria Terminalis (BNST) in Male Rats. Front Neurosci. (2018) Mar 21;12:183. doi: 10.3389/fnins.2018.00183
  • Moaddab M, Dabrowska J. Oxytocin receptor neurotransmission in the dorsolateral bed nucleus of the stria terminalis facilitates the acquisition of cued fear in the fear-potentiated startle paradigm in rats. Neuropharmacology. (2017) 121:130-139.
  • Ryan S, Li C, Menigoz A, Hazra R, Dabrowska J, Ehrlich D, Gordon K, Rainnie DG. Repeated shock stress facilitates basolateral amygdala synaptic plasticity through decreased cAMP-specific phosphodiesterase type IV (PDE4) expression. Brain Struct Funct. (2017) 223:1731-1745.
• Eugene L. Dimitrov
  
  • Cardenas A, Blanca M, Dimitrov E. Persistent pain intensifies recall of consolidated fear memories. Neurobiol Stress. 2019 Apr 10;10:100163. doi: 10.1016/j.ynstr.2019.100163.
  • Paretkar T, Dimitrov E.  The Central Amygdala Corticotropin-releasing hormone (CRH) Neurons Modulation of Anxiety-like Behavior and Hippocampus-dependent Memory in Mice. Neuroscience. 2018 Oct 15;390:187-197. doi: 10.1016/j.neuroscience.2018.08.019.
  • Usdin TB and Dimitrov EL. The Effects of Extended Pain on Behavior: Recent Progress, (2016) Neuroscientist, 22(5):521-33.
• Jeremy Amiel Rosenkranz
  
  • Munshi S, Parrilli V, Rosenkranz JA.  Peripheral anti-inflammatory cytokine Interleukin-10 treatment mitigates interleukin-1β - induced anxiety and sickness behaviors in adult male rats. Behav Brain Res. 2019 Oct 17;372:112024. doi: 10.1016/j.bbr.2019.112024.
  • Blume SR, Padival M, Urban JH, Rosenkranz JA. Disruptive effects of repeated stress on basolateral amygdala neurons and fear behavior across the estrous cycle in rats. Sci Rep. 2019 Aug 23;9(1):12292. doi:10.1038/s41598-019-48683-3.
  • Blume SR, Freedberg M, Vantrease JE, Chan R, Padival M, Record MJ, DeJoseph MR, Urban JH, Rosenkranz JA. Sex- and Estrus-Dependent Differences in Rat Basolateral Amygdala. J Neurosci. 2017 37:10567-10586.
  • Selleck RA, Zhang W, Samberg HD, Padival M, Rosenkranz JA. Limited prefrontal cortical regulation over the basolateral amygdala in adolescent rats. Sci Rep. 2018 Nov 21;8(1):17171. doi: 10.1038/s41598-018-35649-0.
  • Twining RC, Vantrease JE, Love S, Padival M, Rosenkranz JA. An intra-amygdala circuit specifically regulates social fear learning. Nat Neurosci. 2017 20:459-469.

Anxiety - Stress

• Janice H Urban
  • Munshi S, Loh MK, Ferrara N, DeJoseph MR, Ritger A, Padival M, Record MJ, Urban JH, Rosenkranz JA. Repeated stress induces a pro-inflammatory state, increases amygdala neuronal and microglial activation, and causes anxiety in adult male rats. Brain Behav Immun. 2019 Nov 27. pii: S0889-1591(18)30837-7. doi: 10.1016/j.bbi.2019.11.023.
  • Blume SR, Padival M, Urban JH, Rosenkranz JA. Disruptive effects of repeated stress on basolateral amygdala neurons and fear behavior across the estrous cycle in rats. Sci Rep. 2019 Aug 23;9(1):12292. doi:10.1038/s41598-019-48683-3.
  • Silveira Villarroel H, Bompolaki M, Mackay JP, Miranda Tapia AP, Michaelson SD, Leitermann RJ, Marr RA, Urban JH, Colmers WF. NPY Induces Stress Resilience via Downregulation of I(h) in Principal Neurons of Rat Basolateral Amygdala. J Neurosci 38:4505-4520 (2018).
  • Blume SR, Freedberg M, Vantrease JE, Chan R, Padival M, Record MJ, DeJoseph MR, Urban JH, Rosenkranz JA. Sex- and Estrus-Dependent Differences in Rat Basolateral Amygdala. J Neurosci 37:10567-10586 (2017).
  • Leitermann RJ, Rostkowski AB, Urban JH. Neuropeptide Y input to the rat basolateral amygdala complex and modulation by conditioned fear. J Comp Neurol 524:2418-2439 (2016).

Autism

• Jeremy Amiel Rosenkranz
  
  • Twining RC, Vantrease JE, Love S, Padival M, Rosenkranz JA. An intra-amygdala circuit specifically regulates social fear learning. Nat Neurosci. 2017 20:459-469.

Depression

• Eugene L. Dimitrov
  
  • Dimitrov E., Tsuda, M. and Usdin T. B. Anxiety- And Depression-Like Behavior and Impaired Neurogenesis Evoked by Peripheral Neuropathy Persist Following Resolution of Prolonged Tactile Hypersensitivity, (2014) J Neuroscience, 34(37):12304-12.
  • Usdin TB and Dimitrov EL. The Effects of Extended Pain on Behavior: Recent Progress, (2016) Neuroscientist, 22(5):521-33.
• Jeremy Amiel Rosenkranz
  
  • Zhang W, Rosenkranz JA. Effects of Repeated Stress on Age-Dependent GABAergic Regulation of the Lateral Nucleus of the Amygdala. Neuropsychopharmacology. 2016 41:2309-23.
  • Adams T, Rosenkranz JA. Social Isolation During Postweaning Development Causes Hypoactivity of Neurons in the Medial Nucleus of the Male Rat Amygdala. Neuropsychopharmacology. 2016 41:1929-40.
  • Jaisinghani S, Rosenkranz JA. Repeated social defeat stress enhances the anxiogenic effect of bright light on operant reward-seeking behavior in rats. Behav Brain Res. 2015 290:172-9

Pain

• Eugene L. Dimitrov
  • Cardenas A, Caniglia J, Keljalic D, Dimitrov E. Sex Differences in the Development of Anxiodepressive-Like Behavior of Mice Subjected to Sciatic Nerve Cuffing. Pain, March 2020, PMID: 32205527.
  • Paretkar T, Dimitrov E. Activation of enkephalinergic (Enk) interneurons in the central amygdala (CeA) buffers the behavioral effects of persistent pain. Neurobiol Dis. 2019 Apr;124:364-372. doi: 10.1016/j.nbd.2018.12.005.
  • Andreoli M, Marketkar T, Dimitrov E. Contribution of amygdala CRF neurons to chronic pain. (2017) Exp Neurol, 298(Pt A):1-12.
  • Usdin TB and Dimitrov EL. The Effects of Extended Pain on Behavior: Recent Progress, (2016) Neuroscientist, 22(5):521-33.

Reproductive Health

• Janice H Urban
  
  • Woitowich NC, Philibert KD, Leitermann RJ, Wungjiranirun M, Urban JH, Glucksman MJ. EP24.15 as a Potential Regulator of Kisspeptin Within the Neuroendocrine Hypothalamus. Endocrinology. 2016 Feb;157(2):820-30.