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James O'Donnell, PhD

James O'Donnell, PhD
Associate Professor
james.odonnell@rosalindfranklin.edu
Foundational Sciences and Humanities, Cellular and Molecular Pharmacology, Pharmaceutical Sciences
Chicago Medical School, College of Pharmacy
847-578-8673
847-578-3268
Basic Sciences Building, 3.274

Cellular and Molecular Pharmacology Discipline

Publications

Peer-reviewed publications

  1. Mosnaim AD, Wolf ME, III O'Donnell JJ, Hudzik T. β-Phenylethylamine and various monomethylated and para-halogenated analogs. Acute toxicity studies in mice. Drug Chem Toxicol. 2020 Jul;43(4):369-372. doi: 10.1080/01480545.2018.1551899. Epub 2019 Jan 7. PMID: 30614291.
  2. O'Donnell JT, O'Donnell JJ, Vogenberg FR. Forensic Analysis in Drug Litigation Finds Most Errors Occur with Commonly Used Therapies and Practices. P T. 2019 Mar;44(3):118-121. PMID: 30828231; PMCID: PMC6385734.
  3. Tian Y, Gawlak G, O'Donnell III JJ, Birukova AA, Birukov KG. Activation of Vascular Endothelial Growth Factor (VEGF) Receptor 2 Mediates Endothelial Permeability Caused by Cyclic Stretch. J Biol Chem. 2016 May 6;291(19):10032-45. doi: 10.1074/jbc.M115.690487. Epub 2016 Feb 16. PMID: 26884340; PMCID: PMC4858957.
  4. Gawlak G, Son S, Tian Y, O'Donnell III JJ, Birukov KG, Birukova AA. Chronic high-magnitude cyclic stretch stimulates EC inflammatory response via VEGF receptor 2-dependent mechanism. Am J Physiol Lung Cell Mol Physiol. 2016 Jun 1;310(11):L1062-70. doi: 10.1152/ajplung.00317.2015. Epub 2016 Mar 18. PMID: 26993523; PMCID: PMC4935472.
  5. Tian Y, Gawlak G, O'Donnell III JJ, Mambetsariev I, Birukova AA. Modulation of Endothelial Inflammation by Low and High Magnitude Cyclic Stretch. PLoS One. 2016 Apr 29;11(4):e0153387. doi: 10.1371/journal.pone.0153387. PMID: 27128976; PMCID: PMC4851399.
  6. Tian Y, Tian X, Gawlak G, O'Donnell III JJ, Sacks DB, Birukova AA. IQGAP1 regulates endothelial barrier function via EB1-cortactin cross talk. Mol Cell Biol. 2014 Sep 15;34(18):3546-58. doi: 10.1128/MCB.00248-14. Epub 2014 Jul 14. PMID: 25022754; PMCID: PMC4135611.
  7. Gawlak G, Tian Y, O'Donnell III JJ, Tian X, Birukova AA, Birukov KG. Paxillin mediates stretch-induced Rho signaling and endothelial permeability via assembly of paxillin-p42/44MAPK-GEF-H1 complex. FASEB J. 2014 Jul;28(7):3249-60. doi: 10.1096/fj.13-245142. Epub 2014 Apr 4. PMID: 24706358; PMCID: PMC4062829.
  8. Cowan C, Muraleedharan CK, O'Donnell III JJ, Singh PK, Lum H, Kumar A, Xu S. MicroRNA-146 inhibits thrombin-induced NF-κB activation and subsequent inflammatory responses in human retinal endothelial cells. Invest Ophthalmol Vis Sci. 2014 Jul 1;55(8):4944-51. doi: 10.1167/iovs.13-13631. PMID: 24985472.
  9. O'Donnell III JJ, Birukova AA, Beyer EC, Birukov KG. Gap junction protein connexin43 exacerbates lung vascular permeability. PLoS One. 2014 Jun 26;9(6):e100931. doi: 10.1371/journal.pone.0100931. PMID: 24967639; PMCID: PMC4072707.
  10. O'Donnell JT, Marks DH, Danese P, O'Donnell III JJ. Drug-induced liver disease: primer for the primary care physician. Dis Mon. 2014 Feb;60(2):55-104. doi: 10.1016/j.disamonth.2013.11.002. PMID: 24507900.
  11. O'Donnell III JJ, O'Donnell JT, Juettner VM. Clinical pharmacology for the primary care physician. Dis Mon. 2012 Oct;58(10):558-610. doi: 10.1016/j.disamonth.2012.07.003. PMID: 22999026.
  12. O'Donnell III JJ, Zhuge Y, Holian O, Cheng F, Thomas LL, Forsyth CB, Lum H. Loss of p120 catenin upregulates transcription of pro-inflammatory adhesion molecules in human endothelial cells. Microvasc Res. 2011 Sep;82(2):105-12. doi: 10.1016/j.mvr.2011.04.008. Epub 2011 Apr 30. PMID: 21554891; PMCID: PMC3149739.
  13. Zhang J, O'Donnell III JJ, Holian O, Vincent PA, Kim KS, Lum H. P120 catenin represses transcriptional activity through Kaiso in endothelial cells. Microvasc Res. 2010 Sep;80(2):233-9. doi: 10.1016/j.mvr.2010.04.001. Epub 2010 Apr 9. PMID: 20382170; PMCID: PMC2917640.
  14. Jensen, T.R.; O’Donnell III, J. J.; Marks, T.J. 2004.  Do/fn-Mediated Ring-Opening Ziegler Polymerization (ROZP) and Copolymerization with Mono- and Disubstituted Methylenecyclopropanes.  Diverse Mechanisms and a New Chain-Capping Termination Process.   Organometallics. 23(4), 740-754.
  15. Seyam, A.M.; Stubbert, B.D.; Jensen, T.R.; O’Donnell III, J.J.; Stern, C.L.; Marks, T.J. 2004. Organolanthanide Constrained Geometry Complexes Modified for Catalysis: Synthesis, Structure, and Aminoalkane Hydroamination Properties of a Pyrrolidine-substituted Constrained Geometry Organolutetium Complex. Inorganica Chimica Acta, 357, 4029-4035.
  16. C.L.; Marks, T.J. 2004. Organolanthanide Constrained Geometry Complexes Modified for Catalysis: Synthesis, Structure, and Aminoalkane Hydroamination Properties of a Pyrrolidine-substituted Constrained Geometry Organolutetium Complex. Inorganica Chimica Acta, 357, 4029-4035.

Books

  1. O’Donnell III JJ, Somberg J, Idemyor V., O’Donnell JT, Eds. Drug Discovery and Development. Taylor & Francis Publishing. 2020.
  2. O’Donnell, J.T., O’Donnell III, J.J. eds. O’Donnell’s Drug Injury. 4th ed. Tucson, AZ: Lawyers & Judges Publishing Company, Inc.: 2016.

Book Chapters

  1. O’Donnell III JJ, Call GB, “The Pharmacology of Adrenocorticosteroid Disorders”, In: Osborn SI and Wecker L, eds. Brody’s Human Pharmacology, 7th ed. Elsevier, Inc. In press.
  2. O’Donnell III JJ. “Introduction to Endocrine Pharmacology”. In: Osborn S and Wecker L, eds. Brody’s Human Pharmacology, 7th ed. Elsevier, Inc. In press.
  3. O’Donnell III JJ, Somberg J, O’Donnell JT, “Introduction to Drug Discovery and Development”. In: O’Donnell III JJ, Somberg J, Idemyor V., O’Donnell JT, eds. Drug Discovery and Development. Taylor & Francis Publishing. 2020.
  4. O’Donnell JJ, O’Donnell JT. Drug Induced Falls. In Bakken GM, Larue C, Cohen HH, Eds. Slips, Trips, Missteps and Their Consequences. Third Edition. L&J Publ. Tuscon, 2020.
  5. O’Donnell J.T., O’Donnell III, J.J. Pharmacology of Marijuana. In: Nesci J., St. Louis J.P. and Tiftickjian J.M. Medicolegal Aspects of Marijuana Arizona Edition. Tucson, AZ: Lawyers & Judges Publishing Company, Inc.: 2018.
  6. O’Donnell J.T., O’Donnell III, J.J. Marijuana: Pharmacology and Medical-Legal Issues. In: Callahan L.M. and Tiftickjian J.M. Medicolegal Aspects of Marijuana Washington Edition. Tuscon, AZ: Lawyers & Judges Publishing Company, Inc.: 2016.
  7. O’Donnell III, J.J., O’Donnell J.T., and ImObersteg, A.D. Forensic Drug Testing. In: O’Donnell J.T., O’Donnell III, J.J., eds. O’Donnell’s Drug Injury. 4th ed. Tucson, AZ: Lawyers & Judges Publishing Company, Inc.: 2016.
  8. O’Donnell III, J.J., O’Donnell, J.T., Juettner V. General Principles of Pharmacology. In: O’Donnell J.T., O’Donnell III, J.J., eds. O’Donnell’s Drug Injury. 4th ed. Tucson, AZ: Lawyers & Judges Publishing Company, Inc.: 2016.
  9. O’Donnell, J.T., O’Donnell III, J.J. Allergic Drug Reactions. In: O’Donnell J.T., O’Donnell III, J.J. eds. O’Donnell’s Drug Injury. 4th ed. Tucson, AZ: Lawyers & Judges Publishing Company, Inc.: 2016.
  10. O’Donnell, J.T., Marks, D.H., Danese, P., and O’Donnell III, J.J. Drug-induced Liver Disease. In: O’Donnell J.T., O’Donnell III, J.J. eds. O’Donnell’s Drug Injury. 4th ed. Tucson, AZ: Lawyers & Judges Publishing Company, Inc.: 2016.
  11. O’Donnell, J.T., O’Donnell III, J.J. Dangers of Opiates. In: O’Donnell J.T., O’Donnell III, J.J. eds. O’Donnell’s Drug Injury. 4th ed. Tucson, AZ: Lawyers & Judges Publishing Company, Inc.: 2016.
  12. O’Donnell III, J.J., O’Donnell, J.T. Drug-induced Falls. In: O’Donnell J.T., O’Donnell III, J.J., eds. O’Donnell’s Drug Injury. 4th ed. Tucson, AZ: Lawyers & Judges Publishing Company, Inc.: 2016.
  13. O’Donnell III, J.J., O’Donnell, J.T., ImObergsteg, A.D. Drug Testing in the Workplace. In: O’Donnell J.T., O’Donnell III, J.J., eds. O’Donnell’s Drug Injury. 4th ed. Tucson, AZ: Lawyers & Judges Publishing Company, Inc.: 2016.
  14. O’Donnell, J.T., O’Donnell III, J.J. Alcohol. In: O’Donnell J.T., O’Donnell III, J.J., eds. O’Donnell’s Drug Injury. 4th ed. Tucson, AZ: Lawyers & Judges Publishing Company, Inc.: 2016.
  15. O’Donnell, J.T., O’Donnell III, J.J., Benjamin, D.M. Marijuana: Pharmacology and Medical-Legal Issues. In: O’Donnell J.T., O’Donnell III, J.J., eds. O’Donnell’s Drug Injury. 4th ed. Tucson, AZ: Lawyers & Judges Publishing Company, Inc.: 2016.
  16. Benjamin D, O’Donnell JT and O’Donnell JJ. Pharmacology and Toxicology of Marijuana. In: Legal Medicine and Medical Ethics, 9th Edition, American College of Legal Medicine, 2015.
  17. O’Donnell JT and O’Donnell JJ. Pharmacology of Marijuana, in Tiftickjian J. Medical Legal Aspects of Marijuana – Colorado Edition. L&J Publishers, Tucson, 2015.
  18. O’Donnell JT and O’Donnell JJ. Alcohol in Civil Litigation. In: Caplan Y and Goldberger B eds., Garriott’s Medicolegal Aspects of Alcohol, 6th Edition, October 2014.
  19. O’Donnell III J.J., O’Donnell JT, and Juettner VM. 2012. In: Basic Pharmacology in Drug Injury: Liability, Analysis, and Prevention, 3rd Ed. L&J Publ, Tucson, AZ.