View Related Pages
Platelet Auto-antibodies
Principle
In conditions associated with thrombocytopenia, platelet destruction may be mediated by auto-antibodies directed against platelet surface antigens. Although various methods such as radioimmunoassay and enzyme-based assays can detect platelet-associated
Specimen Requirements
Specimen
Whole blood
Collection
Collect 20 mL of blood in a heparinized tube.
Storage and Transport
- Send at room temperature
- Do not refrigerate
- Deliver to the laboratory within 24 hours
Handling
Mix gently after collection to prevent clotting.
Method
Flow Cytometry
Normal Range
Negative
Reported as negative or positive
Turnaround Time
3 business days
References
- Lazarchick, J. and Hall, S. Platelet-associated IgG assay using flow cytometric analysis. J. Immunol. Meth. 87:275, 1986.