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Medical Courses

Medical Neuroscience

MNSC501: Medical Neuroscience: An interdisciplinary introduction to the structure and function of the nervous system team-taught by all faculty members in the Department of Neuroscience, plus several guest clinicians. This course provides a broad overview of modern neuroscience, emphasizing: cellular and molecular neuroscience, including transmitter neurochemistry, neural plasticity, and the biology of neural stem cells;systems neuroscience, focusing on sensory, motor, limbic and higher cognitive systems; neuroanatomy, taught in small-group, case-based sessions utilizing human cadaver brains and interactive computer-based learning; and clinical neuroscience, including correlations on CNS infections, multiple sclerosis, peripheral neuropathy, Parkinson's and Huntington's diseases, disorder of muscle, stroke, brainstem lesions, sleep disorders, schizophrenia, affective disorders, and Alzheimer's disease. Prerequisites: Mammalian Physiology. Spring Quarter, 10 hours per week (7.5 units). Course Director: Lise Eliot, Ph.D.

Sophomore Elective

MNSC603 - Research in Neuroscience: The Department of Neuroscience offers student research training opportunities in a number of disciplines, to be arranged by the faculty advisors. Coordinated by Drs. Marr, Peterson, Stutzmann, West, and Wolf.

MNSC605 - Human Brain Dissection (1 credit): An intensive short course, where students carry out detailed dissections of human cadaver brain, exposing all of the major areas of the forebrain, brainstem, and cerebellum, including major fiber tracts, subcortical nuclei, and their connections to brainstem and cortical structures. Special emphasis will be placed on human limbic structures and the circuitry underlying emotion, addiction, and other psychiatric disorders. Dr. Eliot, Fall quarter, 1 credit. Lab Only.

Graduate Courses

Course Descriptions

GNSC-505 Human Brain Dissection (1 credit): Offered in conjunction with the sophomore medical elective MNSC-605 (see above).

GNSC-599 Pre-candidacy Research in Neuroscience (2.00-12 credits): This course is for the second-year PhD student or third year MD/PhD or DPM-PhD student who has chosen a laboratory but not yet passed the Candidacy Exam. Laboratory experience is geared toward learning techniques and obtaining preliminary data toward the student's dissertation proposal and Candidacy Exam. May be repeated for credit. Fall, Winter, Spring and Summer Quarters, hours and units to be arranged. All Faculty. Lecture Only.

GNSC-553 Neuroscience Journal Club (1 credit): Presentations on current literature, personal research and newsworthy developments in neuroscience by faculty, staff and students. Required of all Neuroscience PhD and MD/PhD students. Fall, Winter and Spring Quarters, one hour per week. Coordinated by Dr. Marr. Seminar/Discussion.

GNSC-570 Neuroscience Teaching Assistant (4 credits): Students will run weekly neuroanatomy discussion sessions for CMS and BMS students enrolled in the Medical Neuroscience course (MNSC-501). Required of all Neuroscience PhD and MD/PhD students during the second and third years of study. Spring Quarter, two hours of teaching per week plus preparation. Coordinated by Dr. Eliot. Seminar/Discussion.

GNSC-600 Neurophysiology (2 credits): A thorough review of neurophysiological function, including the ionic basis of the neuronal membrane potential and action potentials, pre- and post-synaptic signaling, signal transduction, cable properties, and synaptic plasticity. Fall Quarter, two hours per week. Coordinated by Dr. Stutzmann. Seminar/Discussion.

GNSC-605 Techniques in Microscopy (1 credit): A comprehensive instruction to state-of-the-art microscopy and design-based stereology. Lectures cover the fundamentals of tissue preparation and staining, microscopy, digital imaging and confocal stereology. Fall Quarter, 1 credit, Dr. Peterson. Lecture-Lab.

GNSC-606 Neurodegeneration (2 credits): Mechanisms of brain death and neuronal degeneration resulting from chronic or acute diseases and their prospects for recovery. Topics include the clinical features and animal models of traumatic brain injury, stroke, spinal cord injury, Parkinson's, Alzheimer's and Huntington's diseases. Spring Quarter, two hours per week. Coordinated by Drs. Marr and West. Seminar/Discussion.

GNSC-607 Neuronal Signaling (2 credits): This course covers intracellular signaling mechanisms including G proteins, phosphoinositides, cyclic nucleotides, calcium, serine and threonine phosphorylation, and tyrosine phosphorylation. Faculty will present basic information on each topic. Students are responsible for leading discussions based on the text and journal articles. Winter Quarter, two hours per week. Dr. Wolf. Seminar/Discussion.

GNSC-699 Post-candidacy Research in Neuroscience (2-12 credits): This course is for the PhD student who has successfully passed the Candidacy Exam. May be repeated for credit. Fall, Winter, Spring and Summer Quarters, hours and units to be arranged. All Faculty. Research.

GIGP-508 Ethics and Regulatory Issues in Biomedical Research (2 credits): REQUIRED for IGPBS - This course covers most of the major issues related to the responsible conduct of research in the biomedical sciences, including: overt falsification, fabrication, plagiarism (FFP); authorship and publication guidelines; conflict of interest; mentor/trainee responsibilities, and human subject research. Online component includes certification for using radioisotopes and using animals in research. Lecture, discussions, and online modules. Winter quarter. Coordinated by Dr. Eliot.

GIGP-512 Neuroscience Elective for IGPBS (7 credits): This course provides a broad introduction to modern neuroscience, emphasizing: 1) cellular neuroscience, including the neurochemistry of transmitters and receptor function; 2) systems neuroscience, encompassing sensory, motor, affect, memory, language, and other high cognitive functions; 3) human neuroanatomy, taught using a combination of atlases, realistic models, cadaver brains, and interactive computer programs; and 4) clinical neuroscience, focusing on the neurobiological basis of major neurological and psychiatric disorders. Lectures will be supplemented with discussions of recent journal articles. Lecture, lab and discussion. Spring. Coordinated by Dr. Eliot.